Description

5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromo, aminomethyl, and difluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core with further functionalization points.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the halogen and amine groups facilitate downstream coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis, leveraging the aminomethyl group for coordination or tethering.
• Material Science Research: Employed in the development of advanced polymers and functional organic materials that incorporate halogenated aromatic units.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector, enabling the production of bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene
CAS No.	175589-02-3
Molecular Formula	C7H6BrF2N
Molecular Weight	222.03 g/mol
Synonyms	2-(Aminomethyl)-5-bromo-1,3-difluorobenzene; 1-Bromo-2,4-difluoro-6-(aminomethyl)benzene; 5-Bromo-1,3-difluoro-2-(aminomethyl)benzene; Benzenemethanamine, 5-bromo-1,3-difluoro-; (5-Bromo-2,4-difluorophenyl)methanamine; 175589-02-3; 5-Br-2-AMDFB
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Aminomethyl)-1,3-Difluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.