Description

4-Chloro-6-Fluoropyrido[3,4-D]Pyrimidine is a high-value, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique pyridopyrimidine scaffold, functionalized with reactive halogen and fluorine substituents, makes it a critical intermediate for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides with enhanced activity.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating tool compounds to study biological pathways.
• Material Science Research: Investigated as a building block for organic electronic materials and ligands in catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	4-Chloro-6-Fluoropyrido[3,4-D]Pyrimidine
CAS No.	175357-98-9
Molecular Formula	C7H3ClFN3
Molecular Weight	183.57 g/mol
Synonyms	4-Chloro-6-fluoropyrido[3,4-d]pyrimidine; 6-Fluoro-4-chloropyrido[3,4-d]pyrimidine; Pyrido[3,4-d]pyrimidine, 4-chloro-6-fluoro-; 4-Chloro-6-fluoro-1,5-naphthyridine; 175357-98-9; FCAP; 4-Chloro-6-fluoro-pyrido[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoropyrido[3,4-D]Pyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.