Description

2-Methoxy-6-Trifluoromethyl-3H-Pyrimidin-4-One is a high-value, fluorinated pyrimidinone derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and methoxy substitution pattern makes it a versatile intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and CNS-targeted drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a specialized monomer or additive in the synthesis of advanced polymers and functional materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new heterocyclic chemistry and fluorine chemistry.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Methoxy-6-Trifluoromethyl-3H-Pyrimidin-4-One
CAS No.	175354-56-0
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	4(3H)-Pyrimidinone, 2-methoxy-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-methoxy-4(3H)-pyrimidinone; 2-Methoxy-6-trifluoromethylpyrimidin-4(3H)-one; 2-Methoxy-6-(trifluoromethyl)-4(1H)-pyrimidinone; 2-Methoxy-6-(trifluoromethyl)-3H-pyrimidin-4-one; 175354-56-0; 6-Trifluoromethyl-2-methoxy-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-Trifluoromethyl-3H-Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.