Description

n-Methyl-2-(Trifluoromethoxy)Aniline is a specialized aromatic amine derivative featuring a trifluoromethoxy substituent. This compound serves as a versatile and high-value building block in advanced organic synthesis, prized for its unique electronic and steric properties imparted by the fluorine atoms. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials research and development teams seeking to incorporate fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethoxy-aniline pharmacophore.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorinated group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized, high-performance colorants.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing compounds.

Basic Information

Product Name	n-Methyl-2-(Trifluoromethoxy)Aniline
CAS No.	175278-04-3
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-(Trifluoromethoxy)-N-methylaniline; N-Methyl-2-(trifluoromethoxy)benzenamine; 2-(Trifluoromethoxy)-N-methylbenzenamine; 1-Methylamino-2-(trifluoromethoxy)benzene; 2-Methylamino-1-(trifluoromethoxy)benzene; N-Methyl-o-(trifluoromethoxy)aniline; o-(Trifluoromethoxy)-N-methylaniline; 175278-04-3
EINECS	Contact for details

Quality Control

Our n-Methyl-2-(Trifluoromethoxy)Aniline is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.