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2-Amino-6-Fluorobenzylamine CAS NO 175277-93-7


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CAS No.:175277-93-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-6-Fluorobenzylamine is a high-value, multi-functional aromatic amine building block featuring both a primary amine and a benzylamine group on a fluorinated benzene ring. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitors, CNS-active compounds, and fluorinated bioactive molecules.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom and amine functionalities enhance biological activity and stability.
  • Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Polymer Modification: Employed to introduce amine functionality into polymers, resins, and coatings to alter adhesion, cross-linking, and surface properties.
  • Fluorescent Dye and Sensor Development: Acts as a core structure in the design of fluorophores and molecular sensors for analytical and diagnostic applications.
  • Custom Synthesis and R&D: A versatile starting material for contract research organizations and academic laboratories exploring new chemical entities.

Basic Information

Item Detail
Product Name 2-Amino-6-Fluorobenzylamine
CAS No. 175277-93-7
Molecular Formula C7H9FN2
Molecular Weight 140.16 g/mol
Synonyms 2-Amino-6-fluorobenzylamine; (2-Amino-6-fluorophenyl)methanamine; 1-(2-Amino-6-fluorophenyl)methanamine; 6-Fluoro-2-aminobenzylamine; 2-(Aminomethyl)-3-fluoroaniline; Benzenemethanamine, 2-amino-6-fluoro-; α-Amino-2-amino-6-fluorotoluene
EINECS Contact for details

Quality Control

Our 2-Amino-6-Fluorobenzylamine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to light yellow crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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