Description

Cyclopropylmethyl 2-Chloro-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-value pyrimidine-based building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up synthesis for the production of target molecules in pilot plants and commercial manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target compounds.

Basic Information

Product Name	Cyclopropylmethyl 2-Chloro-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	175137-31-2
Molecular Formula	C10H8ClF3N2O2
Molecular Weight	280.63 g/mol
Synonyms	2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylic acid cyclopropylmethyl ester; Cyclopropylmethyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 2-chloro-4-(trifluoromethyl)-, cyclopropylmethyl ester; CPMPC; 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopropylmethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropylmethyl 2-Chloro-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.