Description

5-(Methoxycarbonyl)-4-(Trifluoromethyl)Pyrimidine-2-Hydrazine is a high-value pyrimidine-based building block and intermediate, distinguished by its reactive hydrazine and ester functional groups. This compound is critical for the synthesis of complex heterocyclic molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile precursor for creating complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Material Science: Potential intermediate for the synthesis of specialty polymers and advanced organic electronic materials.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for scale-up and production under cGMP conditions.

Basic Information

Product Name	5-(Methoxycarbonyl)-4-(Trifluoromethyl)Pyrimidine-2-Hydrazine
CAS No.	175137-28-7
Molecular Formula	C8H7F3N4O2
Molecular Weight	248.16 g/mol
Synonyms	Methyl 4-(trifluoromethyl)-2-hydrazinylpyrimidine-5-carboxylate; 2-Hydrazino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid methyl ester; 4-(Trifluoromethyl)-2-hydrazinopyrimidine-5-carboxylic acid methyl ester; 5-Carbomethoxy-4-trifluoromethyl-2-hydrazinopyrimidine; 175137-28-7; Pyrimidine-2-hydrazine, 5-(methoxycarbonyl)-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-(Methoxycarbonyl)-4-(Trifluoromethyl)Pyrimidine-2-Hydrazine adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.