Description

3-Amino-4-(2-Methoxyphenoxy)Benzotrifluoride is a high-value trifluoromethylated aromatic amine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular structure, featuring both an amino group and a benzotrifluoride moiety linked by a methoxyphenoxy bridge, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates for central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments that require high lightfastness and chemical resistance.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	3-Amino-4-(2-Methoxyphenoxy)Benzotrifluoride
CAS No.	175135-08-7
Molecular Formula	C14H12F3NO2
Molecular Weight	283.25 g/mol
Synonyms	3-Amino-4-(2-methoxyphenoxy)-α,α,α-trifluorotoluene; 2-Methoxy-1-(2-amino-5-trifluoromethylphenoxy)benzene; 4-(2-Methoxyphenoxy)-3-aminobenzotrifluoride; 2-Amino-4-(2-methoxyphenoxy)benzotrifluoride; Benzenamine, 4-(2-methoxyphenoxy)-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-4-(2-methoxyphenoxy)aniline
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(2-Methoxyphenoxy)Benzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.