Description

2-Bromo-3,5-Bis(Trifluoromethyl)Aniline is a high-value, multi-functional aromatic amine building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing steric bulk and unique electronic properties into target molecules, enabling the development of advanced materials and pharmaceuticals. It is primarily sought after by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty chemical industries for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting receptors where fluorine substitution is beneficial.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands in catalysis, useful in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or fluorinated polymers, due to its electron-deficient aromatic core.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-3,5-Bis(Trifluoromethyl)Aniline
CAS No.	174824-16-9
Molecular Formula	C9H4BrF6N
Molecular Weight	312.03 g/mol
Synonyms	2-Bromo-3,5-bis(trifluoromethyl)benzenamine; 2-Bromo-α,α,α,α',α',α'-hexafluoro-m-toluidine; 3-Amino-4-bromo-1,5-bis(trifluoromethyl)benzene; 2-Bromo-3,5-di(trifluoromethyl)aniline; 2-Bromo-3,5-bis(trifluoromethyl)phenylamine; Benzenamine, 2-bromo-3,5-bis(trifluoromethyl)-; 2-Br-3,5-(CF3)2C6H2NH2
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,5-Bis(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.