Description

Glycine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-n-[3-[[(2-Propen-1-Yloxy)Carbonyl]Amino]Propyl]- is a specialized, high-purity amino acid derivative designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise, high-yield coupling reactions in controlled environments. It is primarily utilized in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as peptide synthesis and polymer functionalization.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the controlled assembly of complex peptides and proteins.
• Bioconjugation: Used to introduce functional handles (e.g., allyloxycarbonyl groups) onto biomolecules for labeling, cross-linking, or immobilization.
• Polymer Chemistry: Acts as a functional monomer or cross-linker for creating specialty polymers with tailored biological or chemical properties.
• Proteomics Research: Employed in the synthesis of peptide probes, substrates, and inhibitors for enzymatic studies and drug discovery.
• Combinatorial Library Synthesis: A valuable reagent for generating diverse arrays of peptide-based compounds for high-throughput screening.
• Diagnostic Reagent Manufacturing: Used in the production of conjugated peptides for immunoassays and other diagnostic platforms.

Basic Information

Product Name	Glycine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-n-[3-[[(2-Propen-1-Yloxy)Carbonyl]Amino]Propyl]-
CAS No.	174800-19-2
Molecular Formula	C23H24N2O5
Molecular Weight	408.45 g/mol
Synonyms	Fmoc-Glycine(Alloc)-OH; Fmoc-Gly-Alloc-OH; N-Alloc-N-Fmoc-1,3-diaminopropane acetic acid derivative; Nα-Fmoc-Nγ-Alloc-diaminopropionic acid; N-(9-Fluorenylmethoxycarbonyl)-N'-(allyloxycarbonyl)-1,3-diaminopropane-1-carboxylic acid; Fmoc-Dpr(Alloc)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-[(prop-2-en-1-yloxy)carbonylamino]propanoic acid (related isomer); Allyloxycarbonyl-Fmoc protected glycine derivative
EINECS	Contact for details

Quality Control

Our production of this amino acid derivative adheres to stringent Good Manufacturing Practice (GMP) principles where applicable. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets exacting research and production standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by chiral HPLC)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.