Description

Fmoc-Thr((Ac4Galβ1-3)Me,Ac4Neu5Acα2-6Acgalnacα)-Oh CAS NO 174783-92-7 is a complex, protected glycopeptide building block designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for the precise and efficient chemical synthesis of glycoproteins and glycopeptides, enabling researchers to study and mimic complex biological interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on glycobiology, drug discovery, and the development of novel biotherapeutics.

Application

• Glycopeptide & Glycoprotein Synthesis: A key intermediate for the chemical construction of biologically active glycopeptides and glycoprotein mimics.
• Drug Discovery & Development: Used in the research and development of new therapeutic agents, including vaccines, antibodies, and enzyme inhibitors that target carbohydrate-mediated processes.
• Glycobiology Research: Essential for studying the structure, function, and biosynthesis of glycoconjugates in cellular recognition, signaling, and disease mechanisms.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled probes or bioconjugates used in diagnostic assays and imaging studies.
• Synthetic Chemistry Libraries: Enables the generation of diverse glycopeptide libraries for high-throughput screening in pharmaceutical research.

Basic Information

Product Name	Fmoc-Thr((Ac4Galβ1-3)Me,Ac4Neu5Acα2-6Acgalnacα)-Oh
CAS No.	174783-92-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Thr(Ac4Galβ1-3Me, Ac4Neu5Acα2-6AcGalNAcα)-OH; Fmoc-Threonine derivative with protected sialyl-T antigen; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[6-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl-(1→3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl]-(2S,3R)-3-[(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonic acid 4,7,8,9-tetraacetate)-O2-6-yloxy]-2-aminobutanoic Acid; Fmoc-T(Ac4Galβ1-3Me, Ac4Neu5Acα2-6AcGalNAcα); Protected Sialyl-T Antigen Fmoc-Amino Acid.
EINECS	Contact for details

Quality Control

Our Fmoc-Thr((Ac4Galβ1-3)Me,Ac4Neu5Acα2-6Acgalnacα)-Oh is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., argon or nitrogen) when not in use. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMF, DMSO, Acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.