Description

6-Bromo-2-(Methylthio)-4(3H)-Quinazolinone is a versatile and high-value brominated quinazolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and methylthio substituents, makes it a highly reactive and valuable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition, anticancer, and antiviral activities.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Organic Synthesis Building Block: The reactive bromine atom allows for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the methylthio group can be modified or displaced.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Investigated as a monomer or precursor for the development of specialty polymers and organic electronic materials.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	6-Bromo-2-(Methylthio)-4(3H)-Quinazolinone
CAS No.	174313-65-6
Molecular Formula	C9H7BrN2OS
Molecular Weight	271.13 g/mol
Synonyms	6-Bromo-2-(methylthio)-3,4-dihydroquinazolin-4-one; 6-Bromo-2-methylsulfanyl-3H-quinazolin-4-one; 4(3H)-Quinazolinone, 6-bromo-2-(methylthio)-; 2-Methylthio-6-bromo-4(3H)-quinazolinone; 6-Bromo-2-methylmercapto-4(3H)-quinazolinone; 6-Bromo-2-(methylsulfanyl)quinazolin-4(3H)-one; 6-Bromo-2-(methylthio)-4-quinazolinol
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(Methylthio)-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.