Description

Fibronectin Fragment (1371-1382) CAS NO 174063-90-2 is a synthetic peptide fragment derived from the cell adhesion protein fibronectin, specifically corresponding to amino acid residues 1371 to 1382. This bioactive sequence is critical for research into cell-matrix interactions, signal transduction, and the molecular mechanisms of adhesion and migration. It serves as an essential tool for scientists and developers in pharmaceutical R&D, biochemical research, and diagnostic assay development, where precise molecular probes are required.

Application

• Biochemical Research: Used as a specific molecular probe to study integrin binding, cell adhesion mechanisms, and signal transduction pathways.
• Pharmaceutical Development: Serves as a reference standard or active component in the development of novel therapeutics targeting wound healing, angiogenesis, or metastasis.
• Diagnostic Assays: Employed in the development of immunoassays (ELISA) and other diagnostic tests to detect or quantify specific biological interactions.
• Cell Culture & Tissue Engineering: Applied to coat surfaces to promote specific cell attachment and growth in advanced in vitro models.
• Antibody Production & Characterization: Acts as a hapten or antigen for generating and screening monoclonal or polyclonal antibodies with specific epitope recognition.
• Structure-Activity Relationship (SAR) Studies: Utilized as a core sequence for modifying and optimizing peptide-based drug candidates.

Basic Information

Product Name	Fibronectin Fragment (1371-1382)
CAS No.	174063-90-2
Molecular Formula	C62H98N18O19
Molecular Weight	1367.6 g/mol
Synonyms	Fibronectin Cell-Adhesive Peptide; Fibronectin Fragment 1371-1382; Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro; RGDSPASSKP; GRGDSP; Adhesion Peptide; RGD Peptide; Integrin Binding Peptide; FN Fragment (1371-1382); H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH
EINECS	Contact for details

Quality Control

Our Fibronectin Fragment (1371-1382) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) material should be allowed to equilibrate to room temperature in a dry environment before opening to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ±10% of theoretical values
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.