Description

7-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine is a fluorinated tetralin amine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce fluorine atoms and amine functionality into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of novel central nervous system (CNS) agents, receptor modulators, and other fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored electronic or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent markers for biological imaging and diagnostic applications.

Basic Information

Product Name	7-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine
CAS No.	173998-63-5
Molecular Formula	C₁₀H₁₂FN
Molecular Weight	165.21 g/mol
Synonyms	2-Amino-7-fluoro-1,2,3,4-tetrahydronaphthalene; 7-Fluoro-1,2,3,4-tetrahydro-2-naphthylamine; 7-Fluoro-2-tetralinamine; 7-Fluoro-2-aminotetralin; 2-Amino-7-fluorotetralin; 7-Fluoro-2,3-dihydro-1H-inden-2-amine (incorrect but common misnomer); 7-Fluoro-1,2,3,4-tetrahydronaphthalen-2-amine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and acids. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.