Description

Fmoc-Ser(Ac3Fucα)-Oh is a protected, fluorinated carbohydrate-modified amino acid building block, specifically designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for the precise and efficient synthesis of complex glycopeptides, enabling the study of glycosylation's role in biological function and disease. It is an essential reagent for researchers and manufacturers in pharmaceutical development, particularly for creating therapeutic peptides and investigating protein-carbohydrate interactions.

Application

• Glycopeptide Synthesis: A key fluorinated building block for the solid-phase synthesis of O-linked glycopeptides, facilitating the study of fucosylated structures.
• Pharmaceutical R&D: Used in the discovery and development of novel peptide-based therapeutics, vaccines, and diagnostic agents.
• Chemical Biology Probes: Enables the creation of labeled or modified peptides to study enzymatic activity, protein folding, and cell signaling pathways.
• Bioconjugation: Serves as a specialized intermediate for the site-specific modification of proteins and other biomolecules.
• Academic Research: Fundamental tool in laboratories focused on glycoscience, synthetic chemistry, and medicinal chemistry.

Basic Information

Product Name	Fmoc-Ser(Ac3Fucα)-Oh
CAS No.	173935-46-1
Molecular Formula	C32H35F3N2O11
Molecular Weight	680.62 g/mol
Synonyms	Fmoc-Ser(Ac3-α-L-Fuc)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[2,3,4-tri-O-acetyl-α-L-fucopyranosyl]-L-serine; Fmoc-L-Serine, O-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl)-, 9-fluorenylmethyl ester; Fmoc-Ser(Fuc(Ac)3-α)-OH; Fmoc-Ser(O-(2,3,4-tri-O-acetyl-α-L-fucopyranosyl))-OH; Fmoc-Ser(O-Ac3-α-L-Fuc)-OH; Protected Fucosylated Serine Derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Ser(Ac3Fucα)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.