Description

n-Acetyl-Lys-Octreotide is a chemically modified analog of the somatostatin peptide octreotide, featuring an acetylated lysine residue. This modification is critical for enhancing the compound's metabolic stability and receptor binding affinity, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the biopharmaceutical sector for developing targeted therapeutics, particularly for oncology and endocrinology applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel, long-acting somatostatin analogs for therapeutic use.
• Research & Development: Used in preclinical studies to investigate structure-activity relationships (SAR) and optimize peptide drug candidates.
• Radiopharmaceuticals: Acts as a precursor for the development of peptide-based radiopharmaceuticals used in diagnostic imaging and targeted radiotherapy.
• Conjugate Development: The acetylated lysine provides a site for further chemical conjugation with drug payloads, fluorophores, or other functional groups.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	n-Acetyl-Lys-Octreotide
CAS No.	173606-11-6
Molecular Formula	C58H82N14O14S2
Molecular Weight	1223.5 g/mol
Synonyms	Acetyl-Lys-Octreotide; N-Acetyl-Lysine-Octreotide; Octreotide Acetyl-Lysine Derivative; (Ac-Lys)-Octreotide; H-d-Phe-Cys-Phe-d-Trp-Lys(Ac)-Thr-Cys-Thr-ol (disulfide bridge); Somatostatin Analog Ac-Lys Derivative; L-363,301 Acetylated Analog
EINECS	Contact for details

Quality Control

Our n-Acetyl-Lys-Octreotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetic Acid Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.