Description

m-C-Tri(Ch2-Peg1-Nhs Ester) is a heterobifunctional crosslinking reagent featuring an NHS ester group for efficient amine conjugation. This compound is critical for researchers and manufacturers requiring precise, stable bioconjugation in aqueous and biological environments. It is primarily needed by professionals in biopharmaceutical development, diagnostic assay manufacturing, and advanced materials science for creating antibody-drug conjugates (ADCs), protein-polymer hybrids, and functionalized surfaces.

Application

• Bioconjugation & ADC Development: A key reagent for linking cytotoxic drugs, fluorophores, or other payloads to monoclonal antibodies or proteins via amine groups.
• Diagnostic Reagent Synthesis: Used to conjugate enzymes (e.g., HRP, alkaline phosphatase) or other reporter molecules to antibodies or antigens for ELISA and lateral flow assays.
• Polymer & Biomaterial Functionalization: Enables the introduction of bioactive ligands or crosslinking sites onto PEG-based hydrogels, nanoparticles, and other polymeric scaffolds.
• Surface Immobilization: Facilitates the covalent attachment of proteins, peptides, or oligonucleotides to amine-reactive activated surfaces for biosensors and microarrays.
• Protein Labeling & Tracking: Employed for site-specific labeling of proteins with tags for purification, detection, or cellular tracking studies.
• Peptide & Small Molecule Modification: Useful for derivatizing amine-containing peptides or small molecule drugs to enhance solubility, stability, or targeting.

Basic Information

Product Name	m-C-Tri(Ch2-Peg1-Nhs Ester)
CAS No.	173414-89-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	m-C-Tri(Ch2-Peg1-NHS Ester); Tris-PEG1-NHS ester; 1,3,5-Tris(2-(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethoxy)ethyl)benzene; m-PEG3-NHS ester (branched); Heterotrifunctional PEG NHS ester; Amine-reactive tri-branched PEG crosslinker; Benzene-1,3,5-triyltri(ethane-2,1-diyl) tris(2-(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethoxy)acetate)
EINECS	Contact for details

Quality Control

Our m-C-Tri(Ch2-Peg1-Nhs Ester) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and performance for sensitive bioconjugation applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF, acetonitrile
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.