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3-[Ethyl({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl})Amino]Propanoic Acid CAS NO 172965-67-2


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CAS No.:172965-67-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-[Ethyl({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl})Amino]Propanoic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in providing a protected ethylamino propanoic acid side chain, enabling the precise construction of complex peptides and peptidomimetics. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality reagents for producing therapeutic peptides and bioactive compounds.

Application

  • Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of ethylamino propanoic acid motifs into peptide chains.
  • Pharmaceutical Research & Development: Used in the synthesis of novel peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
  • Bioconjugation and Linker Chemistry: Serves as a versatile spacer or functional handle for attaching peptides to other molecules, surfaces, or carriers.
  • Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
  • Production of Custom Peptides: Essential for contract research organizations (CROs) and CDMOs manufacturing bespoke peptides for clients.
  • Academic Research: Used in biochemistry and molecular biology labs to study protein-protein interactions and design novel biomolecules.

Basic Information

Product Name 3-[Ethyl({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl})Amino]Propanoic Acid
CAS No. 172965-67-2
Molecular Formula C20H21NO4
Molecular Weight 339.39 g/mol
Synonyms Fmoc-N-ethyl-β-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-ethyl-β-alanine; Fmoc-N-Et-β-Ala-OH; 3-[(Ethyl-[(9H-fluoren-9-ylmethoxy)carbonyl]amino)]propanoic acid; Nα-Fmoc-N-ethyl-β-alanine; N-Fmoc-N-ethyl-3-aminopropanoic acid; (3-{Ethyl-[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid)
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Quality Control

Our 3-[Ethyl({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl})Amino]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and supply chain traceability for critical R&D and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥98.0%
Water Content (KF) ≤0.5%
Heavy Metals ≤20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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