Description

4-Chloro-2-(2-Hydroxyphenyl)-6-Methylpyrimidine is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the pyrimidine scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Chemical Synthesis: Acts as a versatile electrophile or a functionalized heterocycle in cross-coupling reactions, nucleophilic substitutions, and other advanced organic transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-Chloro-2-(2-Hydroxyphenyl)-6-Methylpyrimidine
CAS No.	172902-25-9
Molecular Formula	C11H9ClN2O
Molecular Weight	220.65 g/mol
Synonyms	4-Chloro-2-(2-hydroxyphenyl)-6-methylpyrimidine; 2-(2-Hydroxyphenyl)-4-chloro-6-methylpyrimidine; 6-Methyl-4-chloro-2-(2-hydroxyphenyl)pyrimidine; 4-Chloro-6-methyl-2-(2-hydroxyphenyl)pyrimidine; 172902-25-9; Pyrimidine, 4-chloro-2-(2-hydroxyphenyl)-6-methyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(2-Hydroxyphenyl)-6-Methylpyrimidine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.