Description

(S)-Methyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-((tert-Butoxycarbonyl)Amino)Hexanoate is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and orthogonal protecting group strategies to build complex biomolecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers developing therapeutic peptides, peptidomimetics, and other bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of peptides, particularly where the side-chain of lysine requires temporary protection.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Research & Development: Used in academic and industrial labs for exploring new peptide structures, studying protein-protein interactions, and developing novel bioconjugates.
• Peptidomimetic Design: Integral for creating modified peptide analogs with enhanced stability, bioavailability, or specific biological activity.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new lead compounds with therapeutic potential.

Basic Information

Product Name	(S)-Methyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-((tert-Butoxycarbonyl)Amino)Hexanoate
CAS No.	172846-56-9
Molecular Formula	C27H34N2O6
Molecular Weight	482.57 g/mol
Synonyms	Fmoc-Lys(Boc)-OH methyl ester; Methyl Nα-Fmoc-Nε-Boc-L-lysinate; Methyl (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate; Fmoc-Lys(Boc)-OMe; Nα-Fmoc-Nε-Boc-L-lysine methyl ester; (S)-Methyl 2-(Fmoc-amino)-6-(Boc-amino)hexanoate; L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-((tert-Butoxycarbonyl)Amino)Hexanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for sensitive peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.