Description

Benzenemethanol, α-Ethyl-3-Fluoro-, (Alphar)- (9Ci) is a high-value, chiral fluorinated benzyl alcohol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise stereochemistry and fluorine substitution make it indispensable for constructing complex molecules with targeted biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique structure enables the fine-tuning of pharmacokinetic and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling high enantioselectivity in critical bond-forming reactions.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where the fluorinated aromatic moiety can modify material properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new fluorination and chiral resolution techniques.

Basic Information

Product Name	Benzenemethanol, α-Ethyl-3-Fluoro-, (Alphar)- (9Ci)
CAS No.	172748-78-6
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	(αR)-α-Ethyl-3-fluorobenzenemethanol; (R)-1-(3-Fluorophenyl)propan-1-ol; (R)-α-Ethyl-3-fluorobenzyl alcohol; (R)-3-Fluoro-α-ethylbenzenemethanol; (R)-1-(3-Fluorophenyl)-1-propanol; (R)-(-)-1-(3-Fluorophenyl)propan-1-ol; Benzenemethanol, α-ethyl-3-fluoro-, (αR)-; (R)-1-(3-Fluorophenyl)propyl alcohol
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, α-Ethyl-3-Fluoro-, (Alphar)- (9Ci) is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) including chiral purity by HPLC is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.