Description

[2-(2-Amino-6-Chloro-9H-Purin-9-Yl)Ethyl]Propanedioic Acid Dimethyl Ester is a high-purity, specialized purine derivative used as a critical pharmaceutical intermediate. This compound matters for its role in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. Pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis specialists need this material for developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside analog prodrugs and related antiviral compounds.
• Antiviral Drug Research: Used in the research and development of novel therapeutics targeting viral polymerases.
• Oncology Research: Serves as a precursor in the development of purine-based chemotherapeutic agents and targeted cancer therapies.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and nucleotide metabolism pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and process development for complex, high-value specialty chemicals.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in medicinal chemistry and drug design.

Basic Information

Product Name	[2-(2-Amino-6-Chloro-9H-Purin-9-Yl)Ethyl]Propanedioic Acid Dimethyl Ester
CAS No.	172529-93-0
Molecular Formula	C₁₃H₁₆ClN₅O₄
Molecular Weight	341.75 g/mol
Synonyms	2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl propanedioic acid dimethyl ester; 2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl malonic acid dimethyl ester; 9-[2-(Methoxycarbonyl)-2-(methoxycarbonylmethyl)ethyl]-6-chloro-9H-purin-2-amine; 6-Chloro-9-[2,2-bis(methoxycarbonyl)ethyl]guanine; 6-Chloro-9-(2,2-dimethoxycarbonylethyl)guanine; CGV Ester; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our [2-(2-Amino-6-Chloro-9H-Purin-9-Yl)Ethyl]Propanedioic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) documenting full specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.