Description

Fibronectin Receptor Peptide (124-131) is a synthetic peptide fragment corresponding to a specific sequence of the fibronectin receptor, also known as integrin α5β1. This compound is a critical research tool for studying cell adhesion, migration, and signaling pathways, as it can competitively inhibit the binding of fibronectin to its receptor. It is primarily utilized by researchers and developers in pharmaceutical discovery, cancer research, and biomaterials science to investigate angiogenesis, metastasis, and tissue engineering applications.

Application

• Biomedical Research: Used as a specific inhibitor to study the role of integrin α5β1 in cell-extracellular matrix interactions.
• Cancer & Metastasis Studies: Applied in assays to investigate tumor cell adhesion, migration, and angiogenesis inhibition.
• Drug Discovery Screening: Serves as a reference standard or active agent in high-throughput screening for anti-adhesion or anti-angiogenic therapeutics.
• Signal Transduction Pathways: Utilized to elucidate downstream signaling events triggered by integrin-ligand binding.
• Biomaterial & Tissue Engineering: Incorporated into surface coatings to modulate cellular responses and improve biocompatibility of implants.
• Inflammation Research: Employed to explore the involvement of integrins in inflammatory cell recruitment and activation.

Basic Information

Product Name	Fibronectin Receptor Peptide (124-131)
CAS No.	172516-80-2
Molecular Formula	C41H68N12O11
Molecular Weight	881.06 g/mol
Synonyms	Fibronectin Cell Attachment Peptide; Arg-Gly-Asp-Ser (RGDS) Peptide; GRGDSP Peptide; GRGDSPK Peptide; Integrin α5β1 Binding Peptide; Adhesion Peptide; CAS 172516-80-2; Cyclo(-Arg-Gly-Asp-D-Phe-Val-)
EINECS	Contact for details

Quality Control

Our Fibronectin Receptor Peptide (124-131) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with detailed specifications for traceability and compliance with research-grade standards. Custom synthesis and purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.