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(2,5-Dibromo-4- Fluoroaniline CAS NO 172377-05-8


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CAS No.:172377-05-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2,5-Dibromo-4- Fluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce bromine and fluorine substituents into complex molecular architectures, enabling the fine-tuning of electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the dibromo-fluoro substitution pattern confers specific biological activity.
  • Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing halogen groups.
  • Dye and Pigment Manufacturing: Acts as a starting material for synthesizing complex, halogenated dyes and pigments with enhanced lightfastness and color properties.
  • Cross-Coupling Reactions: Serves as a versatile substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for constructing biaryl and heteroaryl structures.

Basic Information

Product Name (2,5-Dibromo-4- Fluoroaniline
CAS No. 172377-05-8
Molecular Formula C6H4Br2FN
Molecular Weight 268.91 g/mol
Synonyms 4-Fluoro-2,5-dibromoaniline; 2,5-Dibromo-4-fluoroaniline; 2,5-Dibromo-4-fluoro-benzenamine; 1-Amino-2,5-dibromo-4-fluorobenzene; Benzenamine, 2,5-dibromo-4-fluoro-; Aniline, 2,5-dibromo-4-fluoro-; 4-Fluoro-2,5-dibromo-phenylamine
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Quality Control

Our (2,5-Dibromo-4- Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for fine chemical synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound is light-sensitive (store away from light).

Specification

Item Specification
Appearance Off-white to light brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 72 - 78 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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