Description

3-Fluoro-5-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the fluorine and trifluoromethyl substituents, which are essential for modulating the biological activity and physical characteristics of target molecules. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorinated aromatic core enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, improving the dielectric anisotropy and thermal stability of display components.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, low surface energy, and improved weatherability.
• Organic Electronics: Utilized in the synthesis of charge-transport materials and emitters for OLED (Organic Light-Emitting Diode) applications.
• Chemical Research: A valuable reagent for studying fluorine chemistry, cross-coupling reactions, and as a standard in analytical method development.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Phenol
CAS No.	172333-87-8
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)phenol; 5-Trifluoromethyl-3-fluorophenol; 3-Fluoro-alpha,alpha,α-trifluoro-m-cresol; m-Cresol, 3-fluoro-5-(trifluoromethyl)-; 1-Hydroxy-3-fluoro-5-(trifluoromethyl)benzene; Phenol, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-5-trifluoromethylphenol; 3-Fluoro-5-(trifluoromethyl)benzenol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.