Description

2,4(1H,3H)-Pyrimidinedione, 1-[(2-Hydroxyethoxy)Methyl]-5-(1-Methylethyl)-6-(Phenylseleno)- is a specialized organoselenium derivative of a pyrimidinedione nucleobase analog. This compound matters as a high-value chemical intermediate and research tool, offering unique reactivity for the synthesis of novel nucleoside analogs and potential therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of novel nucleoside analog drugs, particularly for antiviral and anticancer applications.
• Chemical Biology Research: Used as a probe or precursor in studies investigating selenium-modified nucleic acids and their biochemical properties.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug candidate efficacy and selectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organoselenium compounds for specialized applications.
• Academic Research: Utilized in universities and research institutes for fundamental studies in heterocyclic chemistry and bioorganic chemistry.

Basic Information

Item	Detail
Product Name	2,4(1H,3H)-Pyrimidinedione, 1-[(2-Hydroxyethoxy)Methyl]-5-(1-Methylethyl)-6-(Phenylseleno)-
CAS No.	172255-86-6
Molecular Formula	C16H20N2O4Se
Molecular Weight	399.31 g/mol
Synonyms	6-(Phenylseleno)-1-[(2-hydroxyethoxy)methyl]-5-isopropyluracil; 5-Isopropyl-6-(phenylseleno)-1-[(2-hydroxyethoxy)methyl]uracil; 1-[(2-Hydroxyethoxy)methyl]-5-isopropyl-6-(phenylseleno)pyrimidine-2,4(1H,3H)-dione; Selenophenyl-modified isopropyluracil derivative; Organoselenium nucleoside analog; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2,4(1H,3H)-Pyrimidinedione, 1-[(2-Hydroxyethoxy)Methyl]-5-(1-Methylethyl)-6-(Phenylseleno)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request. We support research and development with material that meets high-purity standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.