Description

α-Msh (Human, Mouse, Rat, Porcine, Bovine, Ovine) (Trifluoroacetate Salt) is a high-purity synthetic peptide analog of the endogenous α-melanocyte-stimulating hormone. This compound is critical for research into melanogenesis, inflammation, and appetite regulation due to its potent biological activity across multiple species. It is an essential biochemical tool for pharmaceutical R&D, academic research, and diagnostic development in the life sciences sector.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of skin pigmentation (melanogenesis), anti-inflammatory pathways, and neuroendocrine functions.
• Drug Discovery & Development: Serves as a key pharmacophore and lead compound for developing novel therapeutics targeting melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
• In Vitro & In Vivo Assays: Employed in cell-based assays and animal model studies to investigate its role in energy homeostasis, feeding behavior, and sexual function.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) and other analytical methods to detect and quantify related biomarkers.
• Receptor Binding Studies: Acts as a high-affinity ligand for characterizing melanocortin receptor subtypes and studying signal transduction mechanisms.
• Comparative Physiology: Enables cross-species studies due to its availability in sequences specific to Human, Mouse, Rat, Porcine, Bovine, and Ovine models.

Basic Information

Product Name	α-Msh (Human, Mouse, Rat, Porcine, Bovine, Ovine) (Trifluoroacetate Salt)
CAS No.	171869-93-5
Molecular Formula	C77H109N21O19S • xC2HF3O2
Molecular Weight	~1664.9 g/mol (free base)
Synonyms	α-Melanocyte Stimulating Hormone (1-13) trifluoroacetate salt; α-MSH TFA salt; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 TFA salt; Melanotropin (1-13) TFA; α-MSH (human) acetate; Intermedin; Afamelanotide analog; Melanocortin receptor agonist
EINECS	Contact for details

Quality Control

Our α-Msh (Trifluoroacetate Salt) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC for purity, Mass Spectrometry (MS) for confirmation, and other relevant pharmacopeial tests. We support research and development requiring materials produced in compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak confirmed
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 70.0% (by weight)
Water Content (KF)	≤ 8.0%
Trifluoroacetate Content (HPLC)	≤ 15.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.