Description

2-Methoxy-D-Phenylalanine is a non-natural, chiral amino acid derivative featuring a methoxy substituent on the aromatic ring. This structural modification makes it a valuable key chiral building block for the synthesis of complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) involved in peptide-based drug discovery, medicinal chemistry, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel peptide drugs and peptidomimetics.
• Medicinal Chemistry Research: Used as a chiral scaffold to explore structure-activity relationships (SAR) and develop new therapeutic agents.
• Enzyme Inhibitor Development: Incorporated into compounds designed to selectively inhibit specific enzymes.
• Peptide Synthesis: Serves as a protected or modified amino acid residue in solid-phase and solution-phase peptide synthesis.
• Bioconjugation & Probe Design: Utilized in creating labeled peptides or molecular probes for biochemical assays.
• Academic & Industrial R&D: Employed in research laboratories for studying amino acid chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Methoxy-D-Phenylalanine
CAS No.	170642-31-6
Molecular Formula	C₁₀H₁₃NO₃
Molecular Weight	195.22 g/mol
Synonyms	D-2-Methoxyphenylalanine; (R)-2-Amino-3-(2-methoxyphenyl)propanoic acid; (R)-2-Methoxy-DL-phenylalanine; D-α-Amino-2-methoxyhydrocinnamic acid; H-D-2-MeO-Phe-OH; D-2-Methoxy-Phe; D-2-Methoxyphenylglycine (common misnomer); O-Methyl-D-tyrosine analog
EINECS	Contact for details

Quality Control

Our 2-Methoxy-D-Phenylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.