Description

Fmoc-D-Abu-Oh CAS NO 170642-27-0 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled assembly of complex peptides and peptidomimetics, ensuring precise stereochemistry and chain elongation. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the sequential construction of custom peptide sequences.
• Pharmaceutical Research: Intermediate in the development of novel peptide-based drugs, hormones, and enzyme inhibitors.
• Combinatorial Chemistry: Building block for creating diverse peptide libraries used in high-throughput screening for drug discovery.
• Bioconjugation: Used to introduce specific amino acid functionalities into proteins, antibodies, or other biomolecules.
• Academic & Biochemical Research: For studying protein structure-function relationships, enzyme kinetics, and molecular recognition processes.
• Production of Custom Peptides: Sourced by CROs and CDMOs for the contract manufacturing of research-grade and GMP peptides.

Basic Information

Product Name	Fmoc-D-Abu-Oh
CAS No.	170642-27-0
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Fmoc-D-2-aminobutyric acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-2-aminobutyric acid; Fmoc-D-α-aminobutyric acid; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid; Fmoc-D-Abu-OH; Fmoc-D-But-OH; Fmoc-D-homoalanine; D-Fmoc-aminobutyric acid
EINECS	Contact for details

Quality Control

Our Fmoc-D-Abu-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements, including those for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.