Description

L-Leucine, 2-(Aminomethyl)- (9Ci) CAS NO 170384-28-8 is a specialized, non-proteinogenic amino acid derivative of L-Leucine, featuring an additional aminomethyl group that imparts unique chemical functionality. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, structurally defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other targeted therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate modified leucine residues, altering peptide stability and bioactivity.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme substrate research.
• Ligand Development: Employed in the design and synthesis of novel chelating agents or catalysts for asymmetric synthesis.
• Prodrug Design: Utilized to create amino acid-based prodrugs to improve the solubility, stability, or targeting of active pharmaceutical ingredients.

Basic Information

Product Name	L-Leucine, 2-(Aminomethyl)- (9Ci)
CAS No.	170384-28-8
Molecular Formula	C7H16N2O2
Molecular Weight	160.22 g/mol
Synonyms	2-(Aminomethyl)-L-leucine; (2S)-2-Amino-4-methyl-2-(aminomethyl)pentanoic acid; L-2-(Aminomethyl)leucine; H-Leu(Aminomethyl)-OH; 2-(Aminomethyl)leucine; (S)-2-Amino-4-methyl-2-(aminomethyl)pentanoic acid; 170384-28-8; L-α-(Aminomethyl)leucine
EINECS	Contact for details

Quality Control

Our L-Leucine, 2-(Aminomethyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.