Description

1-Methyl-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is a high-purity, specialized benzodiazepine derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a valuable building block for research into novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents and complex organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs) and investigational drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active compounds.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.
• Organic Synthesis Building Block: Employed in advanced multi-step syntheses to construct complex heterocyclic systems for material science and chemical biology.

Basic Information

Product Name	1-Methyl-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One
CAS No.	170229-03-5
Molecular Formula	C₁₆H₁₄N₂O
Molecular Weight	250.30 g/mol
Synonyms	5-Phenyl-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; 170229-03-5; 1-Methyl-5-phenyl-1,4-benzodiazepin-2(3H)-one; 5-Phenyl-1-methyl-1H-1,4-benzodiazepin-2(3H)-one; 1-Methyl-5-phenyl-3H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Phenyl-1,3-Dihydro-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.