Description

3-Chloro-3'-Fluorobenzhydrol is a high-purity, versatile benzhydrol derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its value lies in providing a functionalized scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals due to its rigid, substituted biphenyl core.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Chloro-3'-Fluorobenzhydrol
CAS No.	170019-18-8
Molecular Formula	C13H10ClFO
Molecular Weight	236.67 g/mol
Synonyms	(3-Chlorophenyl)(3-fluorophenyl)methanol; α-(3-Chlorophenyl)-3-fluorobenzyl alcohol; 1-(3-Chlorophenyl)-1-(3-fluorophenyl)methanol; 3-Chloro-3'-fluoro-diphenylmethanol; 3-Chloro-3'-fluorobenzhydryl alcohol; Benzhydrol, 3-chloro-3'-fluoro-; 3,3'-Difluorochlorobenzhydrol (incorrect but common alias)
EINECS	Contact for details

Quality Control

Our 3-Chloro-3'-Fluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of cGMP and ISO standards for intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.