Description

Fmoc-Phenylalanyl-Glycine CAS NO 169624-67-3 is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precision. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for drug discovery, development of therapeutic peptides, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptide chains using Fmoc (9-fluorenylmethoxycarbonyl) chemistry.
• Pharmaceutical Research: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Bioconjugation: Serves as a component for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Biochemical Reagent: Acts as a substrate or standard in enzymatic studies and analytical method development.
• Custom Peptide Production: A critical raw material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides.

Basic Information

Item	Details
Product Name	Fmoc-Phenylalanyl-Glycine
CAS No.	169624-67-3
Molecular Formula	C26H24N2O5
Molecular Weight	444.48 g/mol
Synonyms	Fmoc-Phe-Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanylglycine; Fmoc-L-Phenylalanyl-Glycine; N-Fmoc-L-phenylalanylglycine; Fmoc-Phenylalanine-Glycine; (2S)-2-[[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-phenylpropanoyl]amino]acetic acid; Fmoc-Phe-Gly; Nα-Fmoc-L-phenylalanylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Phenylalanyl-Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15.0° to -25.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.