Description

4-Amino-7-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity nucleoside analog building block of significant importance in pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel antiviral and anticancer therapeutics, particularly those targeting nucleic acid metabolism. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality raw materials for drug discovery and API synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Antiviral Drug Development: Research and production of active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Precursor for the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and molecular biology assays.
• Process Chemistry: Serves as a starting material for scale-up and optimization of synthetic routes in GMP manufacturing.
• Reference Standard: Qualification as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	4-Amino-7-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	169516-61-4
Molecular Formula	C11H14FN5O4
Molecular Weight	299.26 g/mol
Synonyms	2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl-4-aminopyrrolo[2,3-d]pyrimidine; 4-Amino-7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-F-ara-7-deazaguanine; 2'-F-Arabinosyl-4-aminopyrrolo[2,3-d]pyrimidine; 4-Amino-1-((2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrrolo[2,3-d]pyrimidine; FAAP; Fluorinated nucleoside analog intermediate
EINECS	Contact for details

Quality Control

Our 4-Amino-7-(2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.