Description

1-(3-Fluoro-Benzyl)-Pyrrolidin-3-Ylamine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile amine intermediate, enabling the development of novel compounds with targeted biological activity. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on creating new active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its pyrrolidine-amine scaffold and fluorinated benzyl group.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Chemical Biology & Proteomics: Serves as a valuable building block for creating chemical probes and affinity tags to study enzyme function and protein interactions.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands and catalysts for asymmetric synthesis applications.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers and specialty materials.

Basic Information

Product Name	1-(3-Fluoro-Benzyl)-Pyrrolidin-3-Ylamine Dihydrochloride
CAS No.	169452-20-4
Molecular Formula	C11H16Cl2FN2
Molecular Weight	263.16 g/mol
Synonyms	3-Amino-1-[(3-fluorophenyl)methyl]pyrrolidine dihydrochloride; 1-[(3-Fluorophenyl)methyl]-3-pyrrolidinamine dihydrochloride; 1-(3-Fluorobenzyl)pyrrolidin-3-amine dihydrochloride; 3-Amino-1-(3-fluorobenzyl)pyrrolidine dihydrochloride; 1-(3-Fluorobenzyl)-3-aminopyrrolidine dihydrochloride; 3-Pyrrolidinamine, 1-[(3-fluorophenyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-Benzyl)-Pyrrolidin-3-Ylamine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent customer requirements. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.