Description

Glycine, n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]-n-[[2-Oxo-4-[[(Phenylmethoxy)Carbonyl]Amino]-1(2H)-Pyrimidinyl]Acetyl]- is a specialized, high-purity synthetic amino acid derivative designed for advanced research and pharmaceutical development. This compound is critical for the synthesis of complex peptides and modified oligonucleotides, where precise molecular structure and purity are paramount. It serves as a key building block for researchers and manufacturers in the fields of medicinal chemistry, proteomics, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected amino acid derivative, it is a crucial reagent for the controlled incorporation of modified glycine residues into peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for targeted therapies and biologics.
• Proteomics Research: Employed in the study of protein structure, function, and interactions by enabling site-specific modifications.
• Oligonucleotide Synthesis: Acts as a precursor for creating nucleoside-amino acid conjugates, useful in antisense technology and diagnostic probe development.
• Bioconjugation: Facilitates the covalent attachment of peptides to other molecules, surfaces, or carriers for drug delivery systems and diagnostic assays.
• Chemical Biology Tool Development: Used to create probes and inhibitors for studying enzymatic activity and cellular pathways.

Basic Information

Product Name	Glycine, n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]-n-[[2-Oxo-4-[[(Phenylmethoxy)Carbonyl]Amino]-1(2H)-Pyrimidinyl]Acetyl]-
CAS No.	169396-95-6
Molecular Formula	C32H30N4O7
Molecular Weight	582.61 g/mol
Synonyms	Fmoc-Glycine-(N-Boc-Cytosine) Acetic Acid Ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[2-[[[2-oxo-4-[(phenylmethoxy)carbonyl]amino]-1(2H)-pyrimidinyl]acetyl]amino]ethyl]glycine; Fmoc-Gly-Cyt(Boc)-OH (common abbreviation); Nα-Fmoc-Nω-[[N4-(benzyloxycarbonyl)cytosin-1-yl]acetyl]glycine ethylenediamine derivative; Cytosine-Peptide Conjugate Building Block
EINECS	Contact for details

Quality Control

Our production of this advanced biochemical adheres to stringent quality protocols suitable for research and development applications. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and high purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For extended storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.