Description

(4S)-4-(4-Methylbenzyl)-L-Glutamic Acid CAS NO 169338-17-4 is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced pharmaceutical research and development. This chiral compound serves as a critical synthetic intermediate and building block for the creation of novel therapeutic agents, particularly in the fields of oncology and metabolic disease. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and peptide synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, especially enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used to incorporate unique structural motifs into custom peptides for biological activity studies and drug discovery.
• Medicinal Chemistry Research: Serves as a precursor for creating analogs and derivatives to explore structure-activity relationships (SAR).
• Biochemical Reagent: Employed in enzymatic studies and as a substrate or inhibitor in biochemical assays.
• Fine Chemical Synthesis: A versatile intermediate for the production of complex organic molecules requiring high stereochemical purity.

Basic Information

Product Name	(4S)-4-(4-Methylbenzyl)-L-Glutamic Acid
CAS No.	169338-17-4
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	L-Glutamic acid, 4-[(4-methylphenyl)methyl]-, (4S)-; (S)-4-(4-Methylbenzyl)glutamic Acid; (4S)-4-(p-Methylbenzyl)glutamic Acid; 4-[(4-Methylphenyl)methyl]-L-glutamic acid; (S)-2-Amino-4-(4-methylbenzyl)pentanedioic acid; (4S)-4-(4-Methylbenzyl)glutamic Acid; 169338-17-4; (S)-4-(4-Methylbenzyl)-L-glutamic acid
EINECS	Contact for details

Quality Control

Our (4S)-4-(4-Methylbenzyl)-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.