Description

N4-(3-Bromo-Phenyl)-Quinazoline-4,6-Diamine is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline diamine class. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of targeted kinase inhibitors. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-based drug candidates, especially protein kinase inhibitors.
• Oncology Research: Used in the discovery and development of targeted cancer therapies due to its specific molecular scaffold.
• Biochemical Tool Compound: Serves as a reference standard or a precursor for creating probes in biochemical and pharmacological assays.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) for clinical trials.

Basic Information

Product Name	N4-(3-Bromo-Phenyl)-Quinazoline-4,6-Diamine
CAS No.	169205-78-1
Molecular Formula	C14H11BrN4
Molecular Weight	315.17 g/mol
Synonyms	4,6-Quinazolinediamine, N4-(3-bromophenyl)-; 4-(3-Bromoanilino)quinazoline-6-amine; 6-Amino-4-[(3-bromophenyl)amino]quinazoline; N-(3-Bromophenyl)quinazoline-4,6-diamine; 4,6-Diamino-N-(3-bromophenyl)quinazoline; 169205-78-1; 3-Bromo-N-(6-amino-4-quinazolinyl)aniline
EINECS	Contact for details

Quality Control

Our N4-(3-Bromo-Phenyl)-Quinazoline-4,6-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.