Description

Diethyl 2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Fumarate is a high-purity, specialized pyrimidine derivative with significant synthetic utility. This compound serves as a critical building block in advanced organic synthesis, valued for its unique molecular framework that enables the construction of complex heterocyclic systems. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogs and other potential therapeutic agents targeting viral and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrimidine core for bioactivity.
• Fine Chemical Synthesis: Employed as a versatile scaffold for constructing complex molecules in custom synthesis and process development.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological studies in organic chemistry, including cycloaddition and functionalization reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Diethyl 2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Fumarate
CAS No.	168975-19-7
Molecular Formula	C₁₄H₁₈N₂O₆
Molecular Weight	310.30 g/mol
Synonyms	Diethyl (2E)-2-[(5-Methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)]-2-butenedioate; 1-(3,4-Diethoxycarbonyl-2-butenoyl)-5-methyluracil; 5-Methyl-1-(2-(ethoxycarbonyl)-1-(ethoxycarbonyl)vinyl)uracil; Diethyl (E)-2-((5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl))fumarate; 168975-19-7; 5-Methyl-1-(diethoxycarbonylvinyl)uracil; Fumaric acid, 2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our production of Diethyl 2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Fumarate adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. All materials are fully characterized and tested against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.