Description

Ac-Ile-Tyr-Gly-Glu-Phe-Nh2 is a synthetic hexapeptide amide derivative, featuring an N-terminal acetylation. This compound is of significant interest in biochemical and pharmaceutical research due to its specific peptide sequence, which can serve as a model substrate or a key intermediate in the development of enzyme inhibitors and therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, proteomics, and drug discovery programs.

Application

• Biochemical Research: Used as a standard or reference compound in enzymatic studies and proteomics research.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex peptide-based drug candidates.
• Protease/Enzyme Substrate: Acts as a specific substrate for studying the activity and inhibition of various proteases.
• Peptide Library Construction: Employed in the synthesis of combinatorial peptide libraries for screening biological activity.
• Structure-Activity Relationship (SAR) Studies: Utilized to investigate the relationship between peptide structure and biological function.
• Academic & Institutional Research: Fundamental tool for universities and labs studying peptide chemistry and bioconjugation.

Basic Information

Product Name	Ac-Ile-Tyr-Gly-Glu-Phe-Nh2
CAS No.	168781-78-0
Molecular Formula	C41H56N8O11
Molecular Weight	836.94 g/mol
Synonyms	Acetyl-Isoleucine-Tyrosine-Glycine-Glutamic Acid-Phenylalanine amide; N-Acetyl-L-isoleucyl-L-tyrosylglycyl-L-α-glutamyl-L-phenylalaninamide; Ac-IYGFE-NH2; Ac-ITGFE-NH2; Acetyl Ile-Tyr-Gly-Glu-Phe amide; Hexapeptide-1 (cosmetic ingredient listing); Ac-Ile-Tyr-Gly-Glu-Phe-NH2
EINECS	Contact for details

Quality Control

Our Ac-Ile-Tyr-Gly-Glu-Phe-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.