Description

(Asp371)-Tyrosinase (369-377) (Human) is a synthetic peptide fragment corresponding to a specific epitope of the human tyrosinase enzyme. This high-purity peptide is a critical research tool for immunological studies, particularly in the investigation of melanoma and autoimmune vitiligo. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in T-cell epitope mapping, antibody production, and vaccine research.

Application

• Immunological Research: Used as a defined antigen for studying T-cell responses and immune recognition in melanoma.
• Antibody Development: Serves as an immunogen or screening antigen for generating and characterizing monoclonal and polyclonal antibodies.
• Diagnostic Assay Development: Employed in the development of ELISA, ELISpot, and other immunoassays to detect specific immune reactivity.
• Vaccine Research: Investigated as a potential peptide-based vaccine candidate for cancer immunotherapy targeting tyrosinase.
• Biomarker Studies: Used in research to understand the role of specific tyrosinase epitopes in autoimmune diseases like vitiligo.
• Quality Control Reference: Acts as a reference standard in the quality control of related biological products and assays.

Basic Information

Product Name	(Asp371)-Tyrosinase (369-377) (Human)
CAS No.	168650-46-2
Molecular Formula	C50H75N13O15
Molecular Weight	1082.2 g/mol
Synonyms	Tyrosinase (369-377) (Human) Asp371 variant; HLA-A*0201-restricted tyrosinase peptide; YMDGTMSQV (Asp371); Melanoma antigen peptide; TYR (369-377) peptide; Antigenic peptide Tyr369-377; Synthetic tyrosinase epitope
EINECS	Contact for details

Quality Control

Every batch of (Asp371)-Tyrosinase (369-377) (Human) is manufactured and analyzed under stringent conditions to ensure the highest standard of purity and consistency for research applications. Identity is confirmed by mass spectrometry (MS) and HPLC co-elution. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical composition
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.