Description

Carcinoembryonic Antigen (CEA) is a high-purity glycoprotein biomarker widely used in clinical diagnostics and biomedical research. Its primary commercial value lies in its critical role as a serum tumor marker for monitoring and managing colorectal, pancreatic, and other carcinomas. This reagent is essential for diagnostic kit manufacturers, clinical laboratories, and research institutions focused on oncology and immunology. Consistent quality and batch-to-batch reproducibility are paramount for ensuring reliable assay performance.

Application

• Clinical Immunoassays: Primary calibrant and control material for ELISA, CLIA, and other immunoassay platforms measuring CEA levels in human serum.
• In-Vitro Diagnostic (IVD) Kit Production: A key raw material for the manufacturing of diagnostic kits for cancer screening and monitoring.
• Biomedical Research: Used as a standard in studies investigating tumor biology, metastasis, and the role of CEA in cell adhesion.
• Antibody Development & Validation: Serves as the target antigen for the production, purification, and specificity testing of monoclonal and polyclonal anti-CEA antibodies.
• Quality Control & Proficiency Testing: Employed by reference laboratories to prepare quality control samples and validate testing methodologies.
• Therapeutic Research: Investigated as a target for antibody-drug conjugates (ADCs), cancer vaccines, and other immunotherapeutic approaches.

Basic Information

Product Name	Carcinoembryonic Antigen (CEA)
CAS No.	168635-85-6
Molecular Formula	Contact for details
Molecular Weight	~180-200 kDa (Glycosylated form)
Synonyms	CEA; Carcinoembryonic Antigen; CD66e; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5); Meconium Antigen; Colon Carcinoma Antigen; Tumor-Associated Glycoprotein; Gold Colloid Tumor Marker
EINECS	Contact for details

Quality Control

Our Carcinoembryonic Antigen (CEA) is produced and tested under stringent quality management systems. Each batch is characterized for identity, purity, and immunoreactivity to ensure it meets the exacting requirements of the IVD and research markets. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as purity by SDS-PAGE, concentration, and functional activity in standardized immunoassays. We adhere to relevant ISO 13485 standards for materials intended for diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoassay)	Reacts with specific anti-CEA antibodies
Purity (SDS-PAGE)	> 95%
Protein Content (BCA)	≥ 1 mg/vial (Lot-specific on COA)
Immunological Activity	Fully reactive in reference ELISA
Endotoxin	< 1.0 EU/μg
Solubility	Soluble in PBS or other aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.