Description

2,4(1H,3H)-Pyrimidinedione, 1-(2-Propyn-1-Yl)- is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its reactive alkyne functional group, which enables efficient click chemistry and other coupling reactions to construct complex molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and materials science applications.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Used in the study of enzyme inhibitors and the development of molecular probes.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents.
• Material Science: Employed in the synthesis of functional polymers and advanced organic materials.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 1-(2-Propyn-1-Yl)-
CAS No.	168413-01-2
Molecular Formula	C7H6N2O2
Molecular Weight	150.14 g/mol
Synonyms	1-Propargyluracil; 1-(Prop-2-yn-1-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Propynyl)uracil; Uracil, 1-(2-propynyl)-; 1-Propargyl-2,4-dihydroxypyrimidine; 1-(Prop-2-ynyl)uracil; 1-(Prop-2-yn-1-yl)-1H-pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our production of 2,4(1H,3H)-Pyrimidinedione, 1-(2-Propyn-1-Yl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical research and development projects. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.