Description

(1)Benzothieno(2,3-D)Pyrimidin-4(3H)-One, 5,6,7,8-Tetrahydro-3-Amino-2-(Phenylamino)- is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Used in biochemical assays to study enzyme inhibition mechanisms and cellular signaling pathways.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds with potential biological activity.

Basic Information

Product Name	(1)Benzothieno(2,3-D)Pyrimidin-4(3H)-One, 5,6,7,8-Tetrahydro-3-Amino-2-(Phenylamino)-
CAS No.	168280-54-4
Molecular Formula	C₁₈H₁₈N₄OS
Molecular Weight	338.43 g/mol
Synonyms	5,6,7,8-Tetrahydro-3-amino-2-(phenylamino)benzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; 2-Anilino-3-amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; 3-Amino-2-(phenylamino)-5,6,7,8-tetrahydro-4H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one; Tetrahydro Benzothienopyrimidinone Derivative; BTP Intermediate; Kinase Inhibitor Intermediate CAS 168280-54-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.