Description

n-Me-Tyr(Me)-Oh·Hcl is a protected tyrosine derivative, specifically the hydrochloride salt of N-methyl-O-methyl-L-tyrosine. This modified amino acid building block is critical for advanced peptide synthesis, offering precise control over peptide structure and function. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers in the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled assembly of complex peptide sequences.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used to introduce specific functional handles into peptides for subsequent coupling with dyes, polymers, or other molecules.
• Structure-Activity Relationship (SAR) Studies: Enables the exploration of how methylation at the tyrosine residue affects peptide bioactivity and stability.
• Biochemical Research: Employed in the synthesis of enzyme substrates, inhibitors, and other research tools for proteomics and signal transduction studies.

Basic Information

Product Name	n-Me-Tyr(Me)-Oh·Hcl
CAS No.	168265-06-3
Molecular Formula	C11H15NO3·HCl
Molecular Weight	245.70 g/mol
Synonyms	N-Methyl-O-methyl-L-tyrosine hydrochloride; (S)-2-Amino-3-(4-methoxyphenyl)-2-methylpropanoic acid hydrochloride; H-N-Me-Tyr(Me)-OH·HCl; Fmoc-N-Me-Tyr(Me)-OH·HCl precursor; Boc-N-Me-Tyr(Me)-OH·HCl precursor; Methylated tyrosine derivative HCl salt; Protected tyrosine analog
EINECS	Contact for details

Quality Control

Our n-Me-Tyr(Me)-Oh·Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.