Description

H-Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-Nh2 CAS NO 167875-35-6 is a synthetic heptapeptide featuring a norleucine (Nle) residue and a specific (R)-configuration at the phenylalanine position. This engineered sequence is of significant interest in biochemical and pharmaceutical research for studying peptide structure-activity relationships and receptor interactions. It is primarily utilized by research institutions and biotechnology companies focused on peptide-based drug discovery and development.

Application

• Biochemical Research: Used as a reference standard or tool compound for investigating peptide folding, stability, and bioactivity.
• Pharmaceutical R&D: Serves as a key intermediate or analog in the development of novel therapeutic peptides targeting specific biological pathways.
• Structure-Activity Relationship (SAR) Studies: The inclusion of norleucine and the (R)-Phe configuration makes it valuable for probing the effects of side-chain modifications and stereochemistry on biological function.
• Enzyme Substrate/Inhibitor Studies: Potential use in assays to study protease specificity or to develop enzyme inhibitors.
• Peptide Library Synthesis: Can be incorporated into combinatorial peptide libraries for high-throughput screening.

Basic Information

Item	Detail
Product Name	H-Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-Nh2
CAS No.	167875-35-6
Molecular Formula	C44H73N13O10
Molecular Weight	944.13 g/mol
Synonyms	Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-amide; Heptapeptide H-Arg-Val-Leu-D-Phe-Glu-Ala-Nle-NH2; Norleucine-containing heptapeptide; RVD(R-Phe)EANle-NH2; CAS 167875-35-6; UNII-8F8Q8K179U; (R)-Phe7-Heptapeptide analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. A detailed Certificate of Analysis (COA) providing purity, chromatographic data, and batch-specific information is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.