Description

2-Iodo-L-Phenylalanine is a halogenated derivative of the essential amino acid L-phenylalanine, distinguished by the presence of an iodine atom on the aromatic ring. This modification makes it a valuable non-natural amino acid building block for the synthesis of complex peptides and bioactive compounds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for applications in drug discovery, peptide engineering, and as a precursor for radiopharmaceuticals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including enzyme inhibitors and receptor ligands.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate iodine-labeled amino acids, enabling structure-activity relationship (SAR) studies.
• Radiopharmaceutical Precursor: Serves as a precursor for iodine-123 or iodine-131 labeled compounds used in medical imaging (SPECT) and targeted radiotherapy.
• Biochemical Research: Employed as a probe or tracer in metabolic studies and biochemical assays to investigate protein function and interactions.
• Agrochemical Development: Used in the synthesis of novel compounds with potential herbicidal or pesticidal activity.
• Material Science: Can be incorporated into specialty polymers and advanced materials to impart specific functional properties.

Basic Information

Product Name	2-Iodo-L-Phenylalanine
CAS No.	167817-55-2
Molecular Formula	C9H10INO2
Molecular Weight	291.09 g/mol
Synonyms	(S)-2-Amino-3-(2-iodophenyl)propanoic acid; L-2-Iodophenylalanine; (S)-2-Iodophenylalanine; 2-Iodo-L-α-phenylalanine; 2-Iodo-L-Phe; 2-Iodo-L-Phenylalanine; 2-Iodo-L-Phe-OH; H-2-Iodo-Phe-OH
EINECS	Contact for details

Quality Control

Our 2-Iodo-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.