Description

Fmoc-Asu(Oall)-Oh is a protected amino acid derivative, specifically an Fmoc-protected L-aspartic acid β-allyl ester. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of aspartic acid while protecting its side-chain carboxyl group. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the synthesis of complex peptides, including potential therapeutic agents and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptide chains using Fmoc-chemistry protocols.
• Pharmaceutical Research: Used in the development and production of peptide-based drugs, hormones, and enzyme inhibitors.
• Bioconjugation: The allyl ester protecting group allows for selective deprotection under mild, orthogonal conditions, facilitating site-specific modifications.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse arrays of aspartic acid-containing compounds.
• Biochemical Tool Development: Synthesis of labeled peptides, substrates, or probes for enzymatic and receptor binding studies.
• Academic Research: Fundamental studies in peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Fmoc-Asu(Oall)-Oh
CAS No.	167368-90-3
Molecular Formula	C22H23NO6
Molecular Weight	397.42 g/mol
Synonyms	Fmoc-L-aspartic acid β-allyl ester; Fmoc-Asp(OAll)-OH; N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid 4-allyl ester; Fmoc-Asp-OAll; Fmoc-Asp(Allyl)-OH; Allyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-aspartate; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]butanedioic acid 4-allyl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Asu(Oall)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.