Description

6-Bromo-2-Chloroquinazolin-4(1H)-One is a high-purity halogenated quinazolinone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an invaluable intermediate for the development of novel pharmaceutical compounds, particularly in medicinal chemistry research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides and fungicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Item	Detail
Product Name	6-Bromo-2-Chloroquinazolin-4(1H)-One
CAS No.	167158-70-5
Molecular Formula	C8H4BrClN2O
Molecular Weight	259.49 g/mol
Synonyms	6-Bromo-2-chloro-1,4-dihydroquinazolin-4-one; 6-Bromo-2-chloro-4(1H)-quinazolinone; 2-Chloro-6-bromoquinazolin-4(1H)-one; 4(1H)-Quinazolinone, 6-bromo-2-chloro-; 6-Bromo-2-chloro-3,4-dihydro-4-oxoquinazoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Chloroquinazolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.