Description

3-Quinolinecarboxylic Acid, 8-Bromo-6,7-Difluoro-1-(2-Fluorocyclopropyl)-1,4-Dihydro-4-Oxo-, trans- (9Ci) is a high-purity, multi-functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate or chemical building block, designed to introduce specific halogenated and constrained ring motifs into target molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in antimicrobial or anticancer drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or pesticides, leveraging its unique halogenated quinoline core.
• Chemical Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems in advanced organic and medicinal chemistry.
• Material Science Research: Potential use in the development of specialty chemicals, ligands for catalysis, or functional materials due to its specific fluorine and bromine substitution pattern.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 8-Bromo-6,7-Difluoro-1-(2-Fluorocyclopropyl)-1,4-Dihydro-4-Oxo-, trans- (9Ci)
CAS No.	166973-64-4
Molecular Formula	C13H7BrF3NO3
Molecular Weight	362.10 g/mol
Synonyms	8-Bromo-6,7-difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, trans-; 8-Bromo-6,7-difluoro-1-(2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; trans-8-Bromo-6,7-difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 166973-64-4; 3-Quinolinecarboxylic acid, 8-bromo-6,7-difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, (1R,2S)-rel-; (1R,2S)-rel-8-Bromo-6,7-difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.